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KMID : 1098420130210010054
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Korean Journal of Medicinal Crop Science
2013 Volume.21 No. 1 p.54 ~ p.60
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Screening of Skin Whitening Activity of Codonopsis lanceolata Extract by Complex Steaming Process
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Kim Ji-Seon
Kim Ji-Woong
Kwon Hee-Seok
Lim Hye-won
Lee Hyeon-Yong
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Abstract
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According to previous reports, antioxidant activities of Codonopsis lanceolata could be increased by a steaming process. This study was performed to improve its antioxidant activity and skin whitening activities of C. lanceolata by high pressure and stepwise steaming complex process. The complex processed C. lanceolata showed highest free radical scavenging acitivity as 45.21%, and for phenol and flavonoid contents, complex processed C. lanceolata contained higher than those from conventional extraction process or steaming process alone. The Cytotoxicity of all C. lanceolata extracts also showed low cytotoxicity against human fibroblast cell (CCD-986sk) as 4.49 ~ 10.40%. In whitening activity, high inhibition of tyrosinase activity was estimated as 25.08% by adding the extracts from complex process. We found that whitening and antioxidant activity of complex processed C. lancolata extract was higher than those obtained from conventional extraction and a steaming process because various kinds of antioxidant compounds could be easily released by combined process, compared to one of each process.
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KEYWORD
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High Pressure Process, Stepwise Hot Steaming Process, Antioxidative activity, Skin Whitening, Codonopsis lanceolata
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